Turmeric yog xim daj-txiv kab ntxwv uas los ntawm cov hauv paus hniav ntawm Curcuma longa nroj tsuag. Nws tau siv rau ntau pua xyoo hauv Indian cuisine thiab Ayurvedic tshuaj los kho ntau yam mob. Tsis ntev los no,turmeric extractsstandardized rau high concentrations ntawm curcuminoids tau dhau los ua ib tug nrov khoom noj khoom haus ntxiv txhawb rau ntau yam kev kho mob siv. Tab sis dab tsi yog science tiag tiag hais txog dab tsi turmeric extract yog zoo rau? Cia peb tsom xam cov pov thawj.
Joint Health thiab mob caj dab
Qee qhov kev txhawb nqa kev tshawb fawb muaj zog tshaj plaws rau turmeric extract yog txhawm rau txo qhov mob sib koom tes thiab mob caj dab. Cov khoom tseem ceeb hauv turmeric yog cov nroj tsuag hu ua curcuminoids. Hauv particular, curcuminoid hu ua curcumin qhia cov tshuaj tiv thaiv kab mob thiab antioxidant hauv kev tshawb fawb soj ntsuam.
Piv txwv li, ib 3-hloov kev tshawb fawb hauv cov neeg mob hauv caug osteoarthritis pom tias noj cov tshuaj turmeric extract ntxiv muab 1000 mg ntawm curcumin txhua hnub txo qhov mob pob qij txha thiab txhim kho lub cev ua haujlwm piv rau cov placebo.[1]
Ib yam li ntawd, ib qho kev tshuaj ntsuam xyuas ntawm 8 qhov kev sim tshuaj uas suav nrog yuav luag 1200 tus neeg laus pom cov tshuaj turmeric thiab curcumin kom muaj txiaj ntsig zoo rau kev txo qis cov tsos mob ntawm kev mob caj dab - tshwj xeeb tshaj yog mob pob qij txha - nrog cov teebmeem muaj zog dua ntev dua ntawm kev siv.[2]
Curcumin ntseeg tau tias yuav txo tau cov kab mob xws li mob caj dab, tendinitis thiab bursitis los ntawm kev thaiv cov kab mob pro-inflammatory zoo li TNF-alpha thiab IL-1 beta, thaum txhawb kev tsim cov tshuaj tiv thaiv kab mob ntuj.
Rau Kev Nco thiab Kev Nyuaj Siab
Cov pov thawj loj hlob qhia tau hais tias turmeric kuj tseem tuaj yeem txhawb kev paub txog kev ua haujlwm thiab lub siab lub ntsws - tshwj xeeb tshaj yog thaum nws los txog rau kev nco poob thiab kev nyuaj siab.
Ib txoj kev tshawb fawb nruj me ntsis hauv ib xyoos hauv cov neeg laus dua 60 xyoo nrog kev tsis txaus siab me me tau pom tias noj cov turmeric extract ntxiv nrog 90 mg curcumin ob zaug ib hnub tiv thaiv kev paub tsis meej cuam tshuam nrog kev laus.[4]
Cais, ib qho kev tshuaj ntsuam meta-kev soj ntsuam ntawm 6 qhov kev sim tshuaj pom tau tias cov tshuaj turmeric curcumin xa ntawm 500-1200 mg curcumin txhua hnub ua rau muaj kev cuam tshuam loj heev hauv 6-8 lub lis piam ntawm kev siv.[5] Cov kev xav thiab kev ntxhov siab tswj cov teebmeem tau xav tias yog los ntawm kev txhawb nqa serotonin thiab dopamine ntau lawm - cov neurotransmitters loj uas poob nrog kev laus. [6]
Curcumin ntseeg tau hla cov ntshav-hlwb teeb meem thiab txhawb kev tsim cov hlwb tshiab neuron hlwb hauv hippocampus los piav qhia txog cov txiaj ntsig zoo li neuroprotective hlwb los ntawm cov tshuaj turmeric extract. [7]
Mob plawv Risk Factors
Lub cev loj ntawm tes, tsiaj txhu thiab qee qhov kev tshawb fawb soj ntsuam qhia tau hais tias curcumin los ntawm turmeric qhia ntau yam kev tiv thaiv uas yuav txhais tau tias txo qis kev pheej hmoo ntawm qee cov kab mob ntev - tshwj xeeb tshaj yog kab mob plawv.
Piv txwv li, cov kev tshawb fawb soj ntsuam tau tshaj tawm tias cov tshuaj turmeric thiab curcumin kuj tuaj yeem:
- Txo LDL "phem" cholesterol thiab triglycerides [8]
- Txo cov ntshav siab [9]
- Txhim kho endothelial muaj nuj nqi uas xav tau rau cov hlab ntsha kom zoo [10]
- Txo qhov mob thiab oxidative kev nyuaj siab khi rau atherosclerosis [11]
- Txo qhov tshwm sim ntawm cov ntshav txhaws txaus ntshai [12]
Los ntawm kev cuam tshuam cov no thiab lwm yam kev pheej hmoo, turmeric extract qhia tau tias muaj peev xwm tiv thaiv kev loj hlob ntawm cov kab mob plawv. Txawm hais tias qhov loj dua, kev tshawb fawb ntev ntawm tib neeg tau lees paub ntxiv los txheeb xyuas cov kev tiv thaiv tshwj xeeb rau lub plawv noj qab haus huv.
Nrog rau ntau tshaj 12,000 cov ntawv xov xwm kho mob hais txog curcumin dhau 50 xyoo dhau los, turmeric extract tseem yog ib qho kev tshawb fawb ntau tshaj plaws uas muaj hnub no. Rau kev siv nrog cov ntaub ntawv zoo tshaj plaws hauv tib neeg, turmeric extract standardized rau lub zog muaj zog ntawm curcuminoids xws li curcumin tuaj yeem pab txo qis cov mob - tshwj xeeb tshaj yog cov teeb meem sib koom ua ke xws li osteoarthritis, rheumatoid mob caj dab thiab fibromyalgia. Txhim khu kev nco, txhawb siab, thiab muaj peev xwm tiv thaiv kab mob plawv kuj tshwm sim ntawm cov txiaj ntsig kev tshawb fawb. Txawm hais tias kev tshawb fawb hauv chaw kuaj mob tseem ceeb tshaj tawm cov khoom tiv thaiv kab mob qog noj ntshav, kev kuaj mob ntau dua hauv tib neeg tseem tsim nyog los txhim kho kev siv rau kev tiv thaiv kab mob los yog kev kho mob. Txawm li cas los xij, cov ntaub ntawv pov thawj kev nyab xeeb zoo ua rau turmeric extract yog qhov kev xaiv zoo rau kev tswj hwm ntawm qhov mob thiab mob. Thaum xaiv cov turmeric ntxiv, xyuas kom tseeb tias cov extract tau raug soj ntsuam kom muaj tsawg kawg yog 10 feem pua curcuminoids los lav qhov muaj peev xwm txaus rau cov txiaj ntsig kev noj qab haus huv.
Beton yog tus thawj coj muaj koob npe thiab txawj ntse hauv kev cog qoob loo. Peb cov khoom raug soj ntsuam nruj kom ntseeg tau tias lawv ua tau raws li cov qauv zoo tshaj plaws. Yog tias koj txaus siab rau peb cov khoom, thov koj xav tiv tauj peb ntawmsales@betonnutrition.comtsis muaj hesitation.
Cov ntaub ntawv:
[1] Nakagawa Y, Mukai S, Yamada S.. Cov teebmeem luv luv ntawm cov curcumin uas muaj bioavailable curcumin rau kev kho mob hauv caug osteoarthritis: randomized, ob-dig muag, placebo-tswj kev kawm yav tom ntej. J Orthop Sci. 2014; 19(6):933-9.
[2] Liu Y, Zhang L, Song H.. Kev ua tau zoo thiab kev nyab xeeb ntawm Turmeric thiab Curcumin nyob rau hauv lub hauv caug Osteoarthritis: Ib Meta-Tshaj Tawm ntawm Randomized Placebo-Controlled Trials. Khoom noj khoom haus. 2022; 14(2): 242.
[3] Chandran B, Goel A. A Randomized, Pilot Study los ntsuas qhov ua tau zoo thiab kev nyab xeeb ntawm Curcumin hauv cov neeg mob uas muaj mob caj dab rheumatoid. Phytother Res. 2012; 26(11):1719-25.
[4] Rainey-Smith SR.. Curcumin thiab cognition: ib qho randomised, placebo-tswj, ob-dig muag kev kawm ntawm cov neeg laus hauv zej zog. Br J Nutr. 2016; 115(12):2106-13.
[5] Ng QX.. Clinical Use of Curcumin in Depression: A Meta-Analysis. J Am Med Dir Assoc. 2017;18(6):{5}}.
[6] Lopresti AL. Curcumin rau neuropsychiatric mob: kev tshuaj xyuas hauv vitro, tsiaj txhu thiab tib neeg kev tshawb fawb. J Psychopharmacol. 2019;33(3):{4}}.
[7] Dong S.. Curcumin txhim kho neurogenesis thiab kev paub hauv cov nas hnub nyoog: cuam tshuam rau kev sib cuam tshuam ntawm kev loj hlob thiab synaptic plasticity. PLoS Ib. 2012; 7(2):e31211
[8] Sahebkar A.. Cov txiaj ntsig ntawm curcuminoids ntawm oxidative kev nyuaj siab: Kev tshuaj xyuas thiab kev tshuaj xyuas meta-kev soj ntsuam ntawm randomized tswj kev sim. J Funct Foods. 2015; 18:898-909.
[9] Nelson KM.. Cov teebmeem ntawm curcumin ntxiv rau cov hlab ntsha hauv cov neeg laus uas muaj kev pheej hmoo mob plawv ntxiv: Ib qho randomized, crossover sim. Nutr Metab Cardiovasc Dis. 2022; 32 (5): 1261-1268.
[10] McFarlin BK.. Txo cov nqaij ntshiv thiab nqaij puas tsuaj biomarkers tom qab qhov ncauj supplementation nrog bioavailable curcumin. BBA Clin. 2016; 5:72-78.
[11] Soni KB, Kuttan R. Cov nyhuv ntawm qhov ncauj curcumin kev tswj hwm ntawm cov ntshav peroxides thiab cov roj cholesterol hauv cov neeg tuaj yeem pab dawb. Indian J Physiol Pharmacol. 1992; 36(4):{4}}.
[12] Rashid U, van Reyk DM. Curcumin supplementation txo qis TNF-, IL-6, IL-8, thiab MCP-1 tso tawm hauv cov ntshav qabzib ntau cov kab mob monocytes thiab cov ntshav ntawm TNF-, IL-6, MCP -1, qabzib, thiab glycosylated hemoglobin hauv cov nas ntshav qab zib. Nutr Res. 2011; 31(5):{12}}.
[13] Shehzad, A.. Curcumin hauv kev kho mob qog noj ntshav: cov hom phiaj molecular, pharmacokinetics, bioavailability, thiab kev sim tshuaj. Archiv Pharmazie. 2010; 343(9):{4}}.
[14] Shakibaei M.. Curcumin txhim kho cov nyhuv ntawm cov tshuaj khomob tiv thaiv kab mob qog noj ntshav los ntawm inhibition ntawm NF-κB thiab Src protein kinase signaling pathways. PLoS Ib. 2013;8(2):e57218.
[15] Basile V.. Cov teebmeem ntawm Curcumin hauv Kev Kho Mob Photodynamic: Kev Hloov Kho. Khoom noj khoom haus. Xyoo 2020; 12(3): 852.
[16] Nelson KM.. Kev suav nrog curcumin thiab kua txob dub hauv cov khoom noj hauv qhov ncauj los txhawb kev nqus ntawm qhov ncauj yog unsubstantiated nyob rau hauv tib neeg cov ntaub ntawv soj ntsuam kuaj thiab tsis tsim nyog vim xav tau pharmacological turmeric-tshuaj kev sib cuam tshuam yam tsis tau tsim cov ntaub ntawv kev nyab xeeb: lus. Am J Clin Nutr. 2018; 107(4):{5}}.
[17] James ML, Van Klinken BJW, Bhatt H, Duraisamy S, Duffield M. Curcumin thiab Cancer: Kev nkag siab tam sim no thiab lub sijhawm yav tom ntej. Molecules. 2021; 26(18):5472.
Tib neeg:
Thov sau cov ntsiab lus ntawm cov ntsiab lus tseem ceeb hauv kev tshaj tawm blog.
